Lung Cancer

What is Lung Cancer?

Lung cancer begins when cells in the lungs grow uncontrollably, forming tumors that interfere with the normal breathing process. It typically arises in the lining of the bronchi, bronchioles, or alveoli—parts of the respiratory system responsible for air exchange. 

Lung cancer is one of the leading causes of cancer-related deaths in India and across Asia. While smoking is a major risk factor, lung cancer can also develop in non-smokers. Early detection and specialized treatment play a vital role in improving outcomes. 

Causes and Risk Factors

Several factors increase the risk of lung cancer: 


Smoking

The top risk factor, contributing to over 80% of cases.

 

Passive smoking

Second-hand smoke exposure at home, work, or public places. 

 

Genetic predisposition

Family history and inherited DNA mutations. 

Age

Risk increases with age. 

 

Past lung diseases

TB, bronchitis, and other infections can leave scarring. 

 

Exposure to carcinogens

Includes radon gas, asbestos, air pollution, and arsenic in water. 

 

Radiation exposure

Especially previous radiation therapy to the chest. 

 

Poor diet and lifestyle

Lack of proper nutrition and physical activity. 

Symptoms of Lung Cancer

Symptoms may vary depending on the type and stage of cancer, and they often overlap with other lung diseases.

Early evaluation is key if you notice any of the following:  

Persistent or
worsening cough

Coughing up blood (hemoptysis)

Shortness of breath (dyspnea)

Wheezing or whistling
while breathing 

Hoarseness or
voice changes 

Frequent infections like bronchitis or pneumonia 

Chest, back, or
shoulder pain 

Swelling in the face, arms, or lymph nodes 

Fatigue or unexplained weight loss

Loss of appetite

Fever not responding to regular treatment 

Types of Lung Cancer

Lung cancer is broadly classified into two main categories: 

  1. Non-Small Cell Lung Cancer (NSCLC) – 80–85% of cases  includes: 
  • Adenocarcinoma: Begins in mucus-secreting glands. Common in non-smokers too. 
  • Squamous Cell Carcinoma: Originates in the central bronchi, often linked to smoking. 
  • Large Cell Carcinoma: Aggressive and fast-spreading. Includes subtypes like: 
  • Neuroendocrine carcinoma 
  • Adenosquamous carcinoma 
  • Sarcomatoid carcinoma
  1. Small Cell Lung Cancer (SCLC) – 10–15% of cases 

A fast-growing cancer often diagnosed after it has spread. Responds well to chemotherapy and radiation but has a high recurrence rate. 

Diagnostic Tests for Lung Cancer 

Thangam Hospital offers a full range of advanced diagnostics for lung cancer evaluation: 

  • Physical Examination & History 
  • Chest X-Ray (PA & lateral views) 
  • CT Scan Chest, abdomen, and brain 
  • MRI  To check for metastasis, especially in the brain
  • PET-CT Scan  Assesses spread and staging 
  • Bronchoscopy & EBUS  For airway visualization and biopsy 
  • Sputum Cytology  Microscopic analysis of coughed-up mucus 
  • Lung Biopsy  Confirms cancer type and staging 
  • Molecular Testing  Detects mutations (e.g., EGFR, ALK, PIK3) for targeted therapy 
  • Blood Tests  Evaluate organ function and metabolic markers 
Staging of Lung Cancer ​

Preventing Lung Cancer 

While not all types of lung cancer are preventable, you can significantly reduce your risk by: 

  • Quitting smoking and avoiding tobacco products 
  • Avoiding exposure to second-hand smoke 
  • Eating a nutritious diet rich in antioxidants 
  • Staying physically active and doing breathing exercises 
  • Testing your home for radon and avoiding occupational hazards

Lung cancer is a life-threatening condition, but with early diagnosis, cutting-edge diagnostics, and personalized treatment at Thangam Hospital, patients have a fighting chance at recovery. If you or a loved one show signs of lung cancer, don’t delay—consult our Thoracic Oncology experts today.

Staging of Lung Cancer 

Lung cancer staging is essential for planning treatment. Staging is based on tumor size, lymph node involvement, and metastasis. Tests like PET-CT, EBUS, brain MRI, and biopsy guide the staging process. 

Treatment Options for Lung Cancer 

Thangam Cancer Center offers Comprehensive Thoracic Oncology Care with a multidisciplinary team including oncologists, pulmonologists, thoracic surgeons, radiologists, and palliative care specialists. 

  • Lobectomy or segmental removal of affected lung tissue 
  • Lymph node dissection improves survival chances 
  • Neoadjuvant: Before surgery to shrink the tumor 
  • Adjuvant: Post-surgery to remove residual cancer 
  • Palliative: Advanced stages to relieve symptoms 
  • Used during neoadjuvant, adjuvant, or definitive phases 
  • Effective in managing pain from bone metastases 
  • Personalized medicine targeting specific genetic mutations (e.g., EGFR, ALK) 
  • Minimizes damage to healthy cells 
  • Boosts the body’s immune system to attack cancer 
  • Especially promising in advanced non-small cell lung cancer

Our Oncologists

Dr. Deepan Rajamanickam
Dr. Deepan Rajamanickam
MD, DM

Medical Oncology

Dr. Bhavesh Poladia
Dr. Bhavesh Poladia
DNB, DM

Medical Oncology

Dr. Karthick Rajamanickam
Dr. Karthick Rajamanickam
MD(RT)

Radiation Oncology

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